우울증에서 경두개 자기 자극(Transcranial Magnetic Stimulation)의 치료적

가톨릭대학교 의과대학 정신과학교실 [채종호. 이창욱.  박원명]

 

대한정신약물학회지 : 제 14권 제 2호 2003

 

ABSTRACT :

Therapeutic Application of Transcranial Magnetic Stimulation (TMS) in Depression

 

Jeong-Ho Chae, MD, Chang-UK Lee, MD and Won-Myong Bahk, MD

Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea

 

Objective : Transcranial  magnetic stimulation (TMS) is a new, noninvasive procedure of a localized pulsed magnetic field to the surface of the head to cause a depolarization of neurons in the brain cortex underneath.

Knowledge of the neuroanatomic abnormalities of depression is serving as the background for TMS treatment in depression. Here we provide a summarized review of the therapeutic application of TMS in patients with depression.

Methods: We described the clinical and basic researches of TMS in depression and integrated the future direction using literature review and interview with experts.

Results : The field of TMS is beginning to address the issues of using TMS as a novel antidepressant.

The ability to excite local areas of brain cortex has raised the possibility of the use of TMS as a novel therapeutic tool for depression.

Conclusions : Many parameters, such as intensity, location, frequency, pulse width, intertrain interval, coil type, duration, numbers of sessions, and interval between sessions remain to be systematically explored. However TMS would be a relatively new and noninvasive method to investigate regional brain activity and to treat depression. (Korean J Psychopharmacol 2003;14(2) 77-83)